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The course is centered around different molecules or families of molecules that are relevant to the function of the human body and also its pathology, namely:
  • Hemoglobin, erythropoietin and nitric oxide involved in oxygen transport and vascular regulation
  • Voltage gated potassium channels involved in neuronal and cardiac excitability and associated to long QT syndrome and sudden death
  • Voltage gated calcium channels and calcium pumps (ryanodine receptor and sarcoplasmic reticulum calcium ATPase) involved in muscle contraction and relaxation and associated to malignant hyperthermia
  • G-protein coupled receptors, with special emphasis on beta-adrenergic receptors and angiotensin receptors. Involved in cardiovascular regulation and fluid homeostasis
  • Epithelial sodium channels, involved in cardiorenal regulation
  • Transient-receptor potential channels (TRP) involved in sensory transduction of temperature, pain and mechanical stimulus

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Last updated: 06/26/07