Department of Physics, Chemistry and Biology (IFM)

i)  The Dm-dNK gene is expressed in gene level (60% positives).

ii)  Dm-dNK protein (≈ 28 kDa) expression could be detected only in the skeletal muscle.

iii)  Thymidine phosphorylation higher in Dm-dNK^+/- mice than in wild-type mice.

a. Dm-dNK is highly expressed in kidney, skeletal muscle and brain of Dm-dNK^+/-

mice.

b. Dm-dNK enzyme loses activity after 3 months in brain, and after 5 months in

other tissues.

iv)  There was no change in the mitochondrial DNA levels, mortality, growth rate and organ

weights of the Dm-dNK transgenic mice.