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Publication list for Lars-Göran Mårtensson

Almstedt, K. , Mårtensson, L.-G. , Carlsson, U. and Hammarström, P. 2008. Thermodynamic interrogation of a folding disease. Mutant mapping of position 107 in Human Carbonic Anhydrase II linked to marble brain disease. Biochemistry 47, 1288-1298

Höst, G. , Mårtensson, L.-G . and Jonsson, B.-H. 2006. Redesign of human carbonic anhydrase II for increased esterase activity and specificity towards ester with long acyl chains. Biochimica et Biophysica Acta 1764: 1601-1606

Karlsson, M. , Mårtensson, L.-G . , Karlsson, C. and Carlsson, U. 2005. Denaturant-assisted formation of a disulfide bridge from engineered cysteines in nonideal conformations. Biochemistry 44:3487-3493

Karlsson, M. , Mårtensson, L.-G ., P. Olofsson and Carlsson, U. 2004. Circumnavigating misfolding traps in the energy landscape throough protein engineering:suppression of molten globule and aggregation in carbonic anhydrase. Biochemistry 43:6803-6807

Mårtensson, L.-G ., Karlsson, M. and Carlsson, U.2002.Dramatic stabilization of the native state of human carbonic anhydrase II by an engineered disulfide bond. Biochemistry 41: 15867-15875

Sagermann, M. Mårtensson, L.-G., Baase, W.A. and Matthews, B.W. 2002. A test of proposed rules for helix capping: Implications for protein design. Protein science 11: 516-521

Huber, M., Lindgren, M., Hammarström, P., Mårtensson, L.-G., Carlsson, U., Eaton, G.R. and Eaton, S.S 2001. Phase memory relaxation times in human carbonic anhydrase II: pulsed EPR to determine spin label location. Biophys. Chem. 94: 245-256

Svedhem, S., Enander, K., Karlsson, M., Sjöbom, H., Liedberg, B., Löfås, S., Mårtensson, L.-G., Sjöstrand, S.E., Svensson, S., Carlsson, U. and Lundström, I. 2001. Subtle differences in dissociation rates of interactions between destabilized human carbonic anhydrase II mutants and immobilized benzenesulfonamide inhibitors probed by a surface plasmon resonance biosensor 2001. Anal. Biochem.296: 188-196

Persson, M., Harbridge, J.R., Hammarström, P., Mitri, R., Mårtensson, L.-G., Carlsson, U., Eaton, G.E. and Eaton, S.S. 2001. Comparison of electron paramagnetic resonance methods to determine distances between spin labels on human carbonic anhydrase II. Biophys. J 80:2886-2897

Hammarström, P., Owenius, R., Mårtensson, L.-G., Carlsson, U. and Lindgren, M. 2001. High-resolution probing of local conformational changes in proteins by the use of multiple labeling: Unfolding and self-assambly of human carbonic anhydrase II monitored by spin, fluorescent and chemical reactivity probes. Biophys. J.80: 2867-2885

Karlsson, M., Mårtensson, L-G., Jonsson, B-H. and Carlsson, U 2000 Adsorption of human carbonic anhydrase II variants to silica nanoparticles occur stepwise: Binding is followed by successive conformational changes to a molten globule-like state Langmuir 16:8470-8479

Hammarström, P., Persson, M., Freskgård, P.-O., Mårtensson, L.-G., Andersson, D., Jonsson, B.-H. and Carlsson, U. 1999.Structural mapping of an aggregation nucleation site in a molten globule intermediate. J.Biol. Chem. 274:32897-32903

Svensson, M., Jonasson, P., Freskgård, P.-O., Jonsson, B.-H., Lindgren, M., Mårtensson, L.-G., Gentile, M., Boren, K.and Carlsson, U. 1995. Mapping the folding intermediate of human carbonic anhydrase II: Probing substructure by chemical reactivity and fluorescence labeling of engineered cysteine residues. Biochemistry 34:8606-8620

Lindgren, M., Svensson, M., Freskgård, P.-O., Carlsson, U., Jonasson, P., Mårtensson, L.-G. and Jonsson, B.-H. 1995. Characterization of folding intermediate of human carbonic anhydrase II: pProbing by local mobility by electron paramagnetic resonance. Biophys.J.69: 202-213

Lindgren, M., Svensson, M., Freskgård, P.-O., Carlsson, U., Jonsson, B.-H., Mårtensson, L.-G. and P. Jonasson 1995. Stability measurements on spin labelled mutants of carbonic anhydrase II. EPR characterization of folding intermediates. Magnetic Resonance in Medicine 6:187-189

Aronsson, G, Mårtensson, L.-G., Carlsson, U. and B.-H. Jonsson 1995. Folding of the N-terminus of human carbonic anhydrase II. Biochemistry 34:2153-2162

Mårtensson, L.-G ., Jonasson, P., Jonsson, B.-H., Freskgård, P.-O., Svensson, M. and Carlsson, U. 1995. Contribution of individual tryptophan residues to the fluorescence spectrum of native and denatured forms of human carbonic anhydrase II: Use of acrylamide quenching for structural analysis. Biochemistry 34:1011-1021.

Freskgård, P.-O., Mårtensson, L.-G., Jonasson, P., Jonsson B.-H. and Carlsson, U. 1994. Assignment of the contribution of the tryptophan residues to the circular dichroism spectrum of human carbonic anhydrase II. Biochemistry 33:14281-14288

Mårtensson, L.-G. 1993. Protein folding studies of carbonic anhydrase: Characterization of intermediates by protein engineering and chemical labeling. Doctoral thesis, University of Umeå, ISBN 91-7174-842-3 9

Lindgren, M., Svensson, M., Freskgård, P.-O. Carlsson, U., Jonsson, B.-H., Mårtensson, L.-G. and P. Jonasson 1993. Probing local mobility in carbonic anhydrase. EPR of spin-labeled SH groups introduced by site-directed mutagenesis. J. Chem. Soc. Perkin. Trans.2 2003-2007.

Mårtensson, L.-G ., Jonsson, B.-H., Freskgård, P.-O., Kihlgren, A., Svensson M. and Carlsson, U. 1993 Characterization of folding intermediates of human carbonic anhydrase II. Probing substructure by chemical labeling of SH-groups introduced by site-directed mutagenesis. Biochemistry 32:224-231.

Fransson, C., Freskgård, P.-O., Herbertsson, H., Johansson, Å., Jonasson, P., Mårtensson, L.-G., Svensson, M., Jonsson, B.-H. and Carlsson, U. 1992. Cis-trans isomerization is rate-determining in the reactivation of denatured human carbonic anhydrase II as evidenced by proline isomerase FEBS Lett. 296:90-94

Mårtensson, L.-G ., Jonsson, B.-H., Andersson, M., Kihlgren, A., Bergenhem, N., and Carlsson, U. 1992. Role of an evolutionarily invariant serine for the stability of human carbonic anhydrase II. Biochim. Biophys. Acta 1118:179-186.

Freskgård, P.-O., Carlsson, U.,Mårtensson, L.-G., Jonsson, B.-J. 1991. Folding around the the C-terminus of human carbonic anhydrase II. Kinetic characterization by use of a chemically reactive SH-group introduced by protein engineering. FEBS Lett. 289:117-122.

Andersson, M. Freskgård, P.-O., Kihlgren, A., Bergenhem, N., Carlsson, U., Mårtensson, L.-G. and B.-H. Jonsson. 1991 The effect of substituting histidine 64 in human carbonic anhydrase II on stability of the enzyme. In "Carbonic Anhydrase. From Biochemistry and Genetics to Physiology and Clinical Medicine." (F. Botré, G. Gros, and B.T. Storey, eds.) Verlag Chemie, Weinheim, pp. 119-125.

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Last updated: 05/27/08