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Conclusion


A migration assay was successfully developed, this migration assay allowed investigation of the selective recruitment of PBMCs by macrophages and trophoblasts.

The preliminary results of this study showed that in vitro alternatively activated macrophages, which are phenotypically similar to decidual macrophages, and trophoblasts can recruit monocytes.

Implications

It is essential to understand how normal pregnancy works to be able to fully understand what lies behind pregnancy complications.

This type of research is important to understand cellular functions during normal pregnancy, but also to investigate potentially important molecules which can explain their role in the development of complications during pregnancy.


Responsible for this page: Agneta Johansson
Last updated: 05/17/10