Karin Enander, Ph D
Associate Professor in Molecular Physics, especially Biomolecular Analysis
Director of Centre in Nanoscience and Technology (CeNano)
Division of Molecular Physics
Department of Physics, Chemistry and Biology (IFM)
SE-581 83 Linköping, Sweden
2014- Director of Centre in Nanoscience and Technology (CeNano)
2011- Associate professor and senior lecturer at the Division of Molecular Physics; Department of Physics, Chemistry and Biology; Linköping University; Linköping; Sweden.
2009-2014 Director of Linköping Initiative in Life Science Technologies (LIST)
2006-2010 Assistant professor at the Division of Molecular Physics; Department of Physics, Chemistry and Biology; Linköping University; Linköping; Sweden.
2005 Postdoc at Ecole Supérieure de Biotechnologie de Strasbourg; Université Louis Pasteur; Strasbourg; France.
2004 Postdoc at the Division of Organic Chemistry; Department of Chemistry; Uppsala University; Uppsala; Sweden.
2003 Ph D in Chemistry from the Division of Chemistry; Department of Physics, Chemistry and Biology; Linköping University; Linköping; Sweden.
1999 M Sc in Molecular Biotechnology, Uppsala University, Uppsala, Sweden.
Design and interaction analysis of proteins and peptides, mainly for sensing purposes.
- Peptide and protein production: Chemical synthesis of polypeptides and eukaryotic protein expression (Pichia pastoris)
- Biomoleuclar interaction analysis (mainly by means of surface plasmon resonance and fluorescence spectroscopy techniques)
- Bioassay and protein microarray design
- Design of molecular sensor elements and synthetic receptors
- Nanoparticle-based supramolecular chemistry and plasmonic fluorescence enhancement
- Surface design for cell adhesion studies
- Development of protein immobilization strategies
Halling Linder C, Enander K, Magnusson P: "Glycation contributes to interaction between human bone alkaline phosphatase and collagen type I" Calcif Tissue Int 98:284–293 (2016) Abstract
Aronsson C, Dånmark S, Zhou F, Öberg P, Enander K, Su HB, Aili D: "Self-sorting heterodimeric coiled coil peptides with defined and tuneable self-assembly properties" Scientific Reports 5:14063 (2015) Abstract
Petrone L, Aldred N, Emami K, Enander K, Ederth T, Clare AS: "Chemistry-specific surface adsorption of the barnacle settlement-inducing protein complex" Interface Focus 5:20140047 (2015) Abstract
Selegård R, Enander K, Aili D: "Generic phosphatase activity detection using zinc mediated aggregation modulation of polypeptide-modified gold nanoparticles" Nanoscale 6:14204-14212 (2014) Abstract
Martinsson E, Shahjamali MM, Enander K, Boey F, Xue C, Aili D, and Liedberg B: "Local refractive index sensing based on edge gold-coated silver nanoprisms" Journal of Physical Chemistry C 117: 23148-23154 (2013) Abstract
Ericsson EM, Enander K, Bui L, Lundström I, Konradsson P, and Liedberg B: "Site-specific and covalent attachment of His-tagged proteins by chelation assisted photoimmobilization: A strategy for microarraying of protein ligands" Langmuir 29:11687-11694 (2013) Abstract
Kanmert D, Kastbom A, Almroth G, Skogh T, Enander K, and Wetterö J: "IgG rheumatoid factors against the four human Fc-gamma subclasses in early rheumatoid arthritis (the Swedish TIRA project)" Scandinavian Journal of Immunology 75:115-119 (2012) Abstract
Kanmert D, Brorsson A-C, Jonsson B-H, and Enander K: "Thermal induction of an alternatively folded state in human IgG-Fc." Biochemistry 50:981-988 (2011) Abstract
Choulier L and Enander K: "Environmentally sensitive fluorescent sensors based on synthetic peptides." Sensors 10: 3126-3144 (2010)
Kanmert D, Enocsson H, Wetterö J, Kastbom A, Skogh T, and Enander K: "Designed surface with tunable IgG density as an in vitro model for immune complex mediated stimulation of leukocytes." Langmuir 26: 3493–3497 (2010) Abstract
Aili D, Selegård R, Baltzer L, Enander K, and Liedberg B: "Colorimetric protein sensing by controlled assembly of gold nanoparticles functionalized with synthetic receptors." Small 5:2445-2452 (2009) Abstract
Andersson O, Nikkinen H, Kanmert D, and Enander K: "A multiple-ligand approach to extending the dynamic range of analyte quantification in protein microarrays. " Biosensors and Bioelectronics 24:2458-2464 (2009) Abstract
Carlsson J, Gullstrand C, Westermark G, Ludvigsson J, Enander K, and Liedberg B: "An indirect competitive immunoassay for insulin autoantibodies based on surface plasmon resonance." Biosensors and Bioelectronics 24:882-887 (2008) Abstract
Enander K, Choulier L, Olsson L, Yushchenko D, Kanmert D, Klymchenko A, Demchenko A, Mély Y, and Altschuh D: "A peptide-based, ratiometric biosensor construct for direct fluorescence detection of a protein analyte." Bioconjugate Chemistry 19:1864-1870 (2008) Abstract
Aili D, Enander K, Baltzer L, and Liedberg B: "Assembly of polypeptide-functionalized gold nanoparticles through a heteroassociation- and folding-dependent bridging" Nano Letters 8:2473-2478 (2008) Abstract
Aili D, Tai F-I, Enander K , Baltzer L, and Liedberg B: "Self-assembling fibers and nano-rings from disulphide-linked helix-loop-helix polypeptides." Angewandte Chemie, Int. Ed. 47 :5554-5556 (2008)
Aili D, Enander K, Rydberg J, Nesterenko I, Björefors F, Baltzer L, and Liedberg B: "Folding induced assembly of polypeptide decorated gold nanoparticles." Journal of the American Chemical Society 130 :5780-5788 (2008) Abstract
Aili D, Enander K, Rydberg J, Lundström I, Baltzer L, and Liedberg B: "Aggregation-induced folding of a de novo designed polypeptide immobilized on gold nanoparticles." Journal of the American Chemical Society 128 :2194-2195 (2006) Abstract
Andersson T, Lundquist M, Dolphin G T, Enander K, Jonsson B H, Nilsson J W, and Baltzer L: "The binding of human carbonic anhydrase II by functionalized folded polypeptide receptors." Chemistry and Biology 12:1245-1252 (2005) Abstract
Enander K, Aili D, Baltzer L, Lundström I, and Liedberg B: "Alpha-helix-inducing dimerization of synthetic polypeptide scaffolds on gold." Langmuir 21:2480-2487 (2005) Abstract
Enander K, Dolphin G T, and Baltzer L: "Designed, functionalized helix-loop helix motifs that bind human Carbonic Anhydrase II – a new class of synthetic receptor molecules" Journal of the American Chemical Society 126 :4464-4465 (2004) Abstract
Enander K, Dolphin G T, Liedberg B, Lundström I, and Baltzer L: "A versatile polypeptide platform for integrated recognition and reporting – affinity arrays for protein-ligand interaction analysis" Chemistry – A European Journal 10:2375-2385 (2004) Abstract
Enander K, Andersson L K, Dolphin G T, Liedberg B, Lundström I, and Baltzer L: "Designed, folded polypeptide scaffolds that combine key biosensing events of recognition and reporting" Journal of Organic Chemistry 67:3120-3123 (2002)
Riepl M, Enander K, Liedberg B, Schaferling M, Kruschina M, Ortigao F: "Functionalized surfaces of mixed alkanethiols on gold as a platform for oligonucleotide microarrays" Langmuir 18:7016-7023 (2002)
Svedhem S, Enander K, Karlsson M, Sjöbom H, Liedberg B, Löfås S, Mårtensson L-G, Sjöstrand S-E, Svensson S, Carlsson U, and Lundström I: "Subtle differences in dissociation rates of interactions between destabilized human carbonic anhydrase II mutants and immobilized benzenesulfonamide inhibitors probed by a surface plasmon resonance biosensor" Analytical Biochemistry 296:188-196 (2001) Abstract
Conferences and workshops (oral presentations and proceedings)
Ericsson E M, Bui L, Lundström I, Konradsson P, Liedberg B, and Enander K: Controlled orientation and covalent attachment of proteins on biosensor surfaces by chelation assisted photoimmobilization" Oral presentation, 3rd International Conference in Bio-Sensing Technology, Sitges, Spain, 2013
Enander K: "Protein analyte quantification: concept development" Oral presentation, Taiwan-Sweden Workshop on Nanoscience and Technology, Chi-Tou, Taiwan, 2009
Enander K: "Strategies for improved target quantification in protein microarrays" Invited talk, 2nd Label Free Array Workshop, Paris, France, 2008
Aili D, Han H S, Enander K, Baltzer L, and Liedberg B: "Controlled assembly of gold nanoparticles using de novo designed polypeptide scaffolds" Proceedings of SPIE 6885: 688506 (2008)
Aili D, Enander K, Baltzer L, and Liedberg B: "Synthetic de novo designed polypeptides for control of nanoparticle assembly and biosensing" Biochemical Society Transactions 35:532-534 (2007)
Enander K, Dolphin G T, Lundström I, Liedberg B, and Baltzer L: "De novo designed helix-loop-helix polypeptides – a structure-function-based design strategy for microarray and biosensor applications" Oral presentation, 1st World Congress on Synthetic Receptors, Lisbon, Portugal, 2003
Enander K, Dolphin G T, Löfdahl M, Lundström I, Liedberg B, and Baltzer L: "Designed, folded polypeptides as functional units in surface-based biosensors – versatile scaffolds connecting recognition and reporting" Oral presentation, Europt(r)ode VI, Manchester, UK, 2002
2014- Responsible for the CDIO project course "Materials in Medicine", 6 hp
2006- Course developer and responsible for advanced level course "Proteomics", 6 hp
2006- Guest lecturer in advanced level courses "Biomolecular design", "Biosensor technology", "Methods in biotechnology", "Advanced immunology", "Supramolecular Chemistry", "Modern Sensor Systems"
1999-2002: Assistant in "Principles of Physics", "Biosensor technology", "Surface science", "Biomaterials"
Fluorescence spectroscopy, 8+4 hp
2015- Member of the appointment board at the Engineering Faculty (LiTH)
2012- Member of the Saco-S board at LiU
2009- Member of the programme board for chemistry, biology and biotechnology at the Engineering Faculty (LiTH), with responsibility for the Engineering Biology programme
2007- Member of the LiU board for the Swedish Association of Graduate Engineers (Sveriges Ingenjörer)
2009-2014: Director of Linköping Initiative in Life Science Technologies (LIST)
2007-2009: Involved in the establishment of LiU Junior Faculty and head of the LiTH Junior Faculty steering group (2008-2009)
2005-2010: Project leader of the LiU contribution to "CAREMAN - HealthCARE by Biosensor Measurements And Networking", an EU-funded Integrated Project within the 6th Framework Programme
Responsible for this page: Erik Martinsson
Last updated: 06/28/16